Christina Applegate, a leading MS advocate, says doctors found she doesn’t have the disease after all

(CNN) — Since 2021, Christina Applegate has been one of the most famous advocates for living with multiple sclerosis. Now she says she has discovered that she doesn’t actually have the disease. Applegate shared the shocking news Tuesday during an episode of the podcast she hosts with the actress and MS patient Jamie Lynn Sigler about life with MS, “MeSsy.” Sigler had been hosting the podcast solo for seven months while Applegate dealt with her worsening health. Talking to Sigler in her return appearance, Applegate got emotional when she described how her doctor had told her that recent test results had ruled out the condition. “It’s hard to say, but she came into my room and she said, ‘Congratulations, you don’t have MS.’” Applegate said. “I was like, not happy at all. Everybody else was so happy.” MS is an autoimmune disease in which the immune system attacks the body’s own healthy cells, affecting the nervous system. It can be debilitating for some. For Applegate, her pre